Chloroacetaldehyde Induces Chromosome Aberrations and Micronucleus Formation but Not 2-chloroethanol
نویسندگان
چکیده
منابع مشابه
Chromosome aberrations and micronucleus frequency in anaesthesiology personnel.
Occupational exposure to anaesthetic gases is associated with various adverse health effects. Genetic material is a sensitive target of numerous harmful agents. The aim of this study was to examine whether chromosomal damage could serve to indicate exposure to anaesthetics. Twenty-eight anaesthesiologists, 16 technicians, and 32 control subjects were examined for chromosome aberrations and micr...
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Chromosome segregation defects in cancer cells lead to encapsulation of chromosomes in micronuclei (MN), small nucleus-like structures within which dangerous DNA rearrangements termed chromothripsis can occur. Here we uncover a strikingly different consequence of MN formation in preimplantation development. We find that chromosomes from within MN become damaged and fail to support a functional ...
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The present study aim to examine the cytoprotective effect of herbal drug Cyamopsis tetragonoloba against cisplatin induced Genotoxicity. In the study mice were exposed to cisplatin. MeOH extract of herbal drug C .tetragonoloba (1000-500mg/kg body wt) was administered orally. Bone marrow protection was evaluated by scoring the different type of indusual aberrant, aberrant metaphase and micronuc...
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Blood lymphocytes from xeroderma pigmentosum (XP) and Fanconi anemia (FA) patients were assessed for their sensitivity to ionizing radiation by estimating the frequency of X-ray (1 and 2 Gy)-induced chromosome aberrations (CA). The frequencies of aberrations in the whole genome were estimated in Giemsa-stained preparations of lymphocytes irradiated at G0 or G2 stages. The frequencies of translo...
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ژورنال
عنوان ژورنال: Journal of Health Science
سال: 2011
ISSN: 1344-9702,1347-5207
DOI: 10.1248/jhs.57.300